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Sodium Saccharin only truly became popular during the sugar shortages throughout World War I, even though Sodium saccharin was launched to the public shortly after Sodium saccharin as food sweeteners discovery. Sodium saccharin became even more popular throughout the 1960s and 1970s.
The renal excretion of sodium saccharin infused into adult male and female Sprague- Dawley rats was found to exceed that of inulin at all plasma concentrations. Maximal tubular secretion was clearly demonstrable at a concentration of 14-20 mg/100 mL, and there was no evidence of tubular reabsorption.
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